SPRAVATO® (Esketamine) Treatment at NICA
Now Available for Appropriate Adult Patients
Nursing Infusion Centers of America (NICA) is now offering SPRAVATO®—the only FDA-approved nasal spray for adults with treatment-resistant depression (TRD). This innovative therapy is designed for patients who have not responded to two or more oral antidepressants.
What is SPRAVATO®?
SPRAVATO® (esketamine) is a prescription nasal spray used to treat:
- Treatment-Resistant Depression (TRD) in adults
- Major Depressive Disorder (MDD) with acute suicidal ideation or behavior in adults (when combined with an oral antidepressant)
How SPRAVATO® Works
SPRAVATO® is taken under medical supervision at a REMS-certified treatment center like NICA. It may be taken with or without an oral antidepressant, depending on the treatment plan prescribed by your healthcare provider.
Important Safety Information
- SPRAVATO® is not approved as a pain medication or anesthetic.
- It is not a replacement for hospitalization in cases where immediate psychiatric care is needed.
- It is not approved for children or for long-term prevention of suicidal thoughts or behaviors.
Serious Side Effects May Include:
- Sedation (sleepiness or drowsiness)
- Dizziness or fainting
- Nausea or spinning sensation
- Dissociation (feeling disconnected from yourself, thoughts, space, or time)
- Anxiety or confusion
- Respiratory depression or difficulty breathing
- Abuse, misuse, or dependency
- Increased risk of suicidal thoughts or actions
REMS Program Requirement
Due to potential serious side effects, SPRAVATO® is available only through a restricted program called the SPRAVATO® Risk Evaluation and Mitigation Strategy (REMS) Program. NICA is a certified REMS treatment center and adheres to all monitoring and safety protocols before, during, and after each treatment session.
Why Choose NICA for SPRAVATO®?
- REMS-certified for safe administration
- Experienced behavioral health and medical team
- Comfortable, supervised treatment setting
- Personalized care plans and collaboration with your provider
If you or your provider believe SPRAVATO® may be right for you, please call 866-936-0550 to learn more about our evaluation process and how to begin treatment at NICA.
Getting Started with SPRAVATO® at NICA
At Nursing Infusion Centers of America (NICA), we understand that exploring new treatment options can feel overwhelming. We’re here to support you every step of the way.
Before Treatment: Your First Steps
You can schedule a SPRAVATO® consultation directly with our team to explore if treatment is right for you. You can also speak with your current doctor and have them refer you to us.
To begin, simply complete our Patient Intake Form and we’ll take it from there.
During your initial consultation, a licensed healthcare provider will:
- Review your medical history and treatment goals
- Check your insurance coverage
- Determine if SPRAVATO® is a good fit for your needs
Please note: Treatment is typically not administered during your first visit.
We’ll also coordinate care directly with your referring physician and walk you through the full treatment process so you know exactly what to expect.
What to Expect on Treatment Days
On treatment days, you’ll self-administer the SPRAVATO® nasal spray under the supervision of a trained provider at our center. Afterward, you’ll remain onsite for at least 2 hours so we can safely monitor your:
- Blood pressure
- Oxygen levels (pulse oximetry)
- Overall response
Your comfort and safety are our top priorities during each session.
🚗 After Treatment Care
Because SPRAVATO® can cause drowsiness or dissociation, you should not drive or operate machinery until the next day after a full night of restful sleep.
Treatment typically follows this schedule:
- Weeks 1–4: Twice per week
- Weeks 5–8: Once per week
- Week 9 and beyond: Maintenance frequency decided by you and your provider
Note: SPRAVATO® cannot be used at home. All treatments must take place in our monitored setting.
📞 Ready to Get Started?
We’ll work directly with your insurance to confirm coverage and cost before your first treatment.
To learn more or to schedule a consultation, please call us at 866-936-0550.
We’re here to help you feel better, safely and confidently.